JOB DESCRIPTION
The Childhood Liver Oncology Group (c-LOG) is recruiting a junior researcher in preparation for applying for predoctoral PhD grants.
c-LOG is a young, dynamic and motivated team committed to advancing our understanding of childhood liver cancer. Our focus is on hepatoblastoma, a rare paediatric tumour whose incidence is increasing globally, highlighting the need for further research to improve diagnosis, treatment and outcomes.
Due to its low mutational burden, hepatoblastoma presents unique challenges, requiring researchers to investigate alternative pathways to understand its development. Studying the proteome and tumour microenvironment could lead to the discovery of diagnostic/prognostic biomarkers and therapeutic targets, offering the potential for innovative treatment strategies.
Key areas of interest include:
- Validating diagnostic and prognostic biomarkers of hepatoblastoma and other childhood liver tumours by analysing proteomic databases.
- Glycosylation patterns in hepatoblastoma, which may play a crucial role in tumour biology and progression.
- Integrating the findings with molecular databases generated by the team.
The candidate will conduct this research within the framework of prestigious projects funded by Horizon Europe (THRIVE) and the Scientific Foundation of the Spanish Association Against Cancer (
www.PMed4HB.eu). A major strength of our group is access to a comprehensive and unique biorepository of patient samples collected from across Europe, from the PHITT international clinical trial (Paediatric Hepatic International Tumour Trial, NCT03017326), offering a unique translational research perspective.
The importance of this research is amplified by the limited treatment options currently available for children with advanced or aggressive forms of the disease. Working in this field represents a unique opportunity to contribute to breakthroughs in pediatric oncology.
This PhD opportunity also allows candidates to collaborate with an experienced team on hepatoblastoma research, recognized for significant contributions to the field.
MAIN RESPONSIBILITIES
The candidate will be involved in the ongoing research projects of our group such as:
- Biomarker discovery and validation in retrospective and prospective cohorts from childhood liver cancer patients.
- Study of the proteomic expression profiling in childhood and adult liver cancer.
- Clean, validate, and manage large datasets using Power BI and potentially other relevant data analysis tools.
HOW TO APPLY
Interested persons must attach to the application:
- Motivation letter explaining their interest in the position.
- Updated CV.
- Contact of 2-3 references.
Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:
- Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
- Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.
Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.
DEADLINE FOR APPLICATIONS
The call for applications will close on 6th June 2025.
About us
The Germans Trias i Pujol Research Institute (IGTP) is a public research centre located in Badalona. Its main objective is to increase scientific knowledge in order to transform it into solutions to improve the health and medical care of patients and the community.
The Institute is associated with one of the major university hospitals in the Barcelona area, the Germans Trias i Pujol Hospital, and is part of the Can Ruti biomedical campus. IGTP is a CERCA centre and is also accredited as a centre of excellence by the Instituto de Salud Carlos III (ISCIII) and is in charge of coordinating the management and scientific strategy of the campus, working in close collaboration with the other centres.
The Germans Trias i Pujol Research Institute carries out research within 9 areas:
- Cancer
- Cardiovascular and Respiratory Diseases
- Community Health
- Diseases of the Liver and Digestive Tract
- Endocrine and Diseases of the Metabolism, Bones and Kidneys
- Immunology and Inflammation
- Infectious Diseases
- Neuroscience
- Science of Behaviour and Substance Abuse
Scientists working in these areas publish an average of over 900 papers a year, contribute to improved treatment and healthcare protocols, produce patents and set up spin-off companies in order to improve the lives of patients.
The following video is a bird's eye view of Campus Can Ruti a top-tier translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.
The IGTP, in its commitment to equal opportunities, guarantees equal treatment between candidates and persons with a degree of disability equal to or greater than 33 per 100, as accredited by the Spanish Autonomous Regions or the State Administration, or who have been declared to have a total permanent disability in a different profession through a resolution of the National Institute of Social Security, while retaining functional capacity for the completion of the tasks of the post will be positively considered.