JOB DESCRIPTION
The Immunopathology research group is within the Immunology Service of the Germans Trias Hospital. It is made up of an experienced interdisciplinary team that is highly motivated to carry out translational research and give support to clinical teams who are developing their own research projects to examine the mechanisms of the immune response.
The team is made up of researchers, pre-doctoral researchers and technicians who carry out prestigious research projects in the national and international arenas. The laboratory is one of 14 centres of European excellence recognized by the Federation of Clinical Immunological Societies (FOCIS). Since 2009 it is a Consolidated Group as recognized by the Agency for Management of University and Research Grants of the Generalitat of Catalonia.
The current project will be ascribed to the Neuroimmunology team. Since 2008 the Neuroimmunology team has been developing new immune tolerance-inducing therapies, and recently finished a Phase I clinical trial with tolerogenic dendritic cells (VitD3tolDC) in multiple sclerosis patients that showed safety and feasibility of the approach. It coordinated a European network consisting of the most important groups in the field of tolerogenic cellular therapies for autoimmunity, and transplants in the field (European Action COST BM1305-AFACTT) ( www.cost.eu).
We are looking for a highly motivated and skilled postdoctoral researcher to work on a project entitled: “Advanced Antigen-Specific Dendritic cells based therapy to re-establish tolerance in immune-mediated diseases” (IMMUTOL), funded by the HORIZON-HLTH-2022-DISEASE-06-02 Program.
This project aims to generate a more powerful second generation engineered VitD3tolDC product for its translation to the clinic.
MAIN RESPONSIBILITIES
The postdocoral researcher will participate in the bulk RNAseq, methylation and single cell RNAseq analysis of the therapeutic effect of engineered tolerogenic dendritic cells in an experimental model of multiple sclerosis (experimental autoimmune encephalomyelitis -EAE-).
QUALIFICATIONS AND EXPERIENCIE
REQUIRED QUALIFICATIONS AND SKILLS:
- PhD in Biosciences
- Passion for research
- Strong background in bioinformatics
- Research Planning and Organization skills
- Project management
- Good command of written and spoken English
- Team player with good communication skills.
- To contribute, with the principal investigator to the mentoring and supervision of master and/or PhD students.
- It is expected that the candidate contributes to writing of scientific manuscripts with the outcomes of her/his research.
Additional skills will be also considered such as:
- Experience in cellular and molecular immunology
- Motivation for learning and continuous improvement of skills and scientific growth
- Good knowledge on the field of immune tolerance
HOW TO APPLY
Interested persons must attach to the application:
- Motivation letter explaining their interest in the position.
- Updated CV.
- Contact of 2-3 references.
Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:
a) Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
b) Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.
Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.
DEADLINE FOR APPLICATIONS
The call will be open until Desember, 10th, 2024
About us
The Germans Trias i Pujol Research Institute (IGTP) is a public research centre located in Badalona. Its main objective is to increase scientific knowledge in order to transform it into solutions to improve the health and medical care of patients and the community.
The Institute is associated with one of the major university hospitals in the Barcelona area, the Germans Trias i Pujol Hospital, and is part of the Can Ruti biomedical campus. IGTP is a CERCA centre and is also accredited as a centre of excellence by the Instituto de Salud Carlos III (ISCIII) and is in charge of coordinating the management and scientific strategy of the campus, working in close collaboration with the other centres.
The Germans Trias i Pujol Research Institute carries out research within 9 areas:
- Cancer
- Cardiovascular and Respiratory Diseases
- Community Health
- Diseases of the Liver and Digestive Tract
- Endocrine and Diseases of the Metabolism, Bones and Kidneys
- Immunology and Inflammation
- Infectious Diseases
- Neuroscience
- Science of Behaviour and Substance Abuse
Scientists working in these areas publish an average of over 900 papers a year, contribute to improved treatment and healthcare protocols, produce patents and set up spin-off companies in order to improve the lives of patients.
The following video is a bird's eye view of Campus Can Ruti a top-tier translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.
The IGTP, in its commitment to equal opportunities, guarantees equal treatment between candidates and persons with a degree of disability equal to or greater than 33 per 100, as accredited by the Spanish Autonomous Regions or the State Administration, or who have been declared to have a total permanent disability in a different profession through a resolution of the National Institute of Social Security, while retaining functional capacity for the completion of the tasks of the post will be positively considered.
